Exercise in NAFLD: Just do it

Shelley E. Keatinga,, Leon A. Adamsb

Abstract

The health burden of non-alcoholic fatty liver disease (NAFLD) is multifaceted. In addition to sequelae of end-stage liver disease and hepatocellular carcinoma, the deleterious role of hepatic steatosis in the development of type 2 diabetes and cardiovascular disease is also well established.NAFLD affects up to one third of the adult population and may become more prevalent with the escalation of obesity globally. Therefore, there is an urgent need for effective therapies for not only reducing steatosis and liver injury, but for improving insulin resistance and the cardiovascular risk associated with NAFLD.